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TP53 — TRIM28
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
TRIM28
—
TP53
(physical association, affinity chromatography technology)
Gilmore-Hebert et al., Mol Cancer Res 2010*
-
IRef Biogrid Interaction:
TRIM28
—
TP53
(physical association, affinity chromatography technology)
Okamoto et al., Biochem Biophys Res Commun 2006*
-
IRef Biogrid Interaction:
TRIM28
—
TP53
(direct interaction, enzymatic study)
Doyle et al., Mol Cell 2010
-
IRef Intact Interaction:
Complex of UBA1-TRIM28-TP53-UBE2H-MAGEC2
(association, ubiquitinase assay)
Doyle et al., Mol Cell 2010
-
IRef Intact Interaction:
Complex of MAGEC2-TRIM28-TP53
(association, pull down)
Doyle et al., Mol Cell 2010
-
IRef Intact Interaction:
Complex of TRIM28-TP53-MAGEA2B-MAGEA2
(association, pull down)
Doyle et al., Mol Cell 2010
-
IRef Intact Interaction:
Complex of 244 proteins
(association, pull down)
Komarova et al., Mol Cell Proteomics 2011
Text-mined interactions from Literome
Wang et al., EMBO J 2005
:
Depletion of endogenous
KAP1 expression by RNAi
stimulates p53 transcriptional activity, sensitizes p53 response to DNA damage, and increases apoptosis ... Therefore, MDM2 interaction with
KAP1 contributes to
p53 functional regulation
Okamoto et al., Biochem Biophys Res Commun 2006
(Neoplasms) :
We examined the
role of
KAP1 in
p53 activation after the treatment of cells with different types of external stresses