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BRCA1 — PGR

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: BRCA1 — PGR (direct interaction, pull down) Ma et al., Mol Endocrinol 2006*
• IRef Biogrid Interaction: BRCA1 — PGR (physical association, affinity chromatography technology) Ma et al., Mol Endocrinol 2006*
• IRef Biogrid Interaction: BRCA1 — PGR (direct interaction, enzymatic study) Calvo et al., Cancer Res 2011*

Text-mined interactions from Literome

Ma et al., Mol Endocrinol 2006 : The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells
Katiyar et al., Nuclear receptor signaling 2006 : Regulation of progesterone receptor signaling by BRCA1 in mammary cancer
Katiyar et al., Mol Endocrinol 2009 : Mechanism of BRCA1 mediated inhibition of progesterone receptor transcriptional activity ... Previously, we reported that BRCA1 inhibits progesterone receptor (PR) activity and blocks progesterone stimulated gene expression and cell proliferation
Calvo et al., Cancer Res 2011 (Breast Neoplasms...) : BRCA1 counteracts progesterone action by ubiquitination leading to progesterone receptor degradation and epigenetic silencing of target promoters