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ADM — TNF

Text-mined interactions from Literome

Isumi et al., FEBS Lett 1999 : We demonstrated that adrenomedullin (AM) inhibited interleukin-1beta induced tumor necrosis factor-alpha (TNF-alpha) secretion and gene transcription in Swiss 3T3 fibroblasts maximally to 23 % and 18 % of control, while the other peptides elevating intracellular cAMP levels elicited much weaker effects
Udono et al., Invest Ophthalmol Vis Sci 2000 : Regulation of the ADM expression by basic fibroblast growth factor, interferon (IFN)-gamma, tumor necrosis factor-alpha , interleukin (IL)1beta, or all-trans-retinoic acid was studied
Hofbauer et al., Hypertension 2002 : For this purpose, we characterized the effects of inflammatory cytokines, tumor necrosis factor-alpha ( 100 microg/L ), interleukin-1beta ( 20 microg/L ), and interferon-gamma ( 0.5 U/L ) on ADM gene expression in rat aortic vascular smooth muscle cells ( AVSMCs )
Wang et al., Zhonghua Wai Ke Za Zhi 2007 (Carcinoma, Hepatocellular...) : To investigate the reversal of multidrug resistance in the cell line HepG2/ADM induced by TNF-alpha
Okura et al., Arthritis Res Ther 2008 (Arthritis, Experimental) : Analysis of mRNA levels showed that adrenomedullin significantly reduced TNFalpha mRNA expression by 21 % to 49 % in a dose dependent manner, and dose-dependently increased IL-6 mRNA expression by 45 % to 121 %
Han et al., Zhonghua Wai Ke Za Zhi 2009 (Disease Models, Animal) : ADM can reduce the expression of TNF-alpha
Liao et al., Horm Metab Res 2013 : The effects of TNF-a and EDN-1 on ADM gene expression and secretion were also investigated ... As TNF-a also increases ADM levels in the epididymal fat and the soleus muscle and EDN-1 also increases ADM levels in the epididymal fat, they may form a feedback loop with ADM in these tissues
Chini et al., Kidney Int 1997 : MC grown in primary culture synthesized ADM , and the synthesis was stimulated by TNF alpha and IL-1 beta but not by PDGF and EGF