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HMOX1 — HMOX2

Text-mined interactions from Literome

Mazza et al., J Appl Physiol 2001 (Anoxia) : Together, these results indicate that HO-2 is present in the RVLM under control conditions and that HO-1 is induced in the RVLM during chronic hypoxia, consistent with a potential role for HO in the oxygen sensing function of these cardiorespiratory RVLM regions
Guo et al., Life Sci 2001 (Brain Injuries...) : There are three isoforms of HO : HO-1 is highly inducible , whereas HO-2 and HO-3 are constitutively expressed
Goldstein et al., J Neurosci Res 2003 (Cerebral Hemorrhage) : Heme oxygenase-2 was constitutively expressed by these cells, and heme oxygenase-1 was induced by hemin
Stanford et al., Eur J Pharmacol 2003 : Many cell types express heme oxygenase-2 constitutively while heme oxygenase-1 is induced at sites of inflammation and oxidative stress ... Here, using primary cultures of human pulmonary artery smooth muscle cells, we present novel data showing that this cell type expresses heme oxygenase-2 constitutively and, in the presence of oxidants, can induce heme oxygenase-1
Ding et al., FEBS J 2006 : Down-regulation of HO-2 expression with siRNA against HO-2 ( siHO-2 ) caused induction of HO-1 expression at both mRNA and protein levels in HeLa and HepG2 cells
Seta et al., Am J Pathol 2006 (Inflammation...) : HO-2 deletion was associated with impaired HO-1 induction, indicating that HO-2 is critical for HO-1 expression and that the subsequent failure to up-regulate the HO system may contribute to unresolved inflammation and the development of chronic inflammatory conditions
Parfenova et al., Curr Pharm Des 2008 (Brain Injuries...) : Rapid activation of HO-2 via post-translational modifications without upregulation of HO-2 expression or HO-1 induction coincides with the increase in cerebral blood flow aimed at maintaining brain homeostasis and neuronal survival during seizures, hypoxia, and hypotension
Bau et al., Purinergic Signal 2005 : These data demonstrate that guanosine enhances NGF dependent neurite outgrowth by first activating the constitutive isozyme HO-2 , and then by inducing the expression of HO-1 , the enzymes responsible for CO synthesis, thus stimulating sGC and increasing intracellular cGMP
Yilmaz et al., Photosynth Res 2010 : We report that HO2 , the protein encoded by ho2, was induced in the cells growing under a microaerobic atmosphere [ 0.2 % ( v/v ) O ( 2 ) ], whereas HO1 was constitutively expressed under both aerobic and microaerobic atmospheres
Lämsä et al., Chem Res Toxicol 2010 : Both CYP2A5 and HMOX1 were induced by all three compounds ; however, HMOX1 responded more rapidly and transiently as compared to CYP2A5
Ewing et al., Brain Res Brain Res Protoc 1997 : HO-2 is a constitutive protein and its expression is not affected by the inducers of HO-1 tested to date ; rather, the only known regulator of HO-2 yet identified is adrenal glucocorticoids