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CAV1 — IGF1R
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Stewart et al., Crit Rev Oncol Hematol 2010
(Carcinoma, Non-Small-Cell Lung...) :
Limited early clinical data suggest that chemotherapy resistance in NSCLC may also be increased with decreased expression of cyclin B1 or of Eg5, or with increased expression of ICAM, matrilysin, osteopontin, DDH, survivin, PCDGF,
caveolin-1 , p21WAF1/CIP1, or 14-3-3sigma, and that
IGF-1R inhibitors may
increase efficacy of chemotherapy, particularly in squamous cell carcinomas
Martins et al., PloS one 2011
(Sarcoma, Ewing) :
We observed that
IGF1R is internalized upon ligand binding in ES cells and that this process is
dependent on clathrin or
CAV1