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BCL10 — IL6
Text-mined interactions from Literome
Puthier et al., Br J Haematol 1999
(Multiple Myeloma) :
In a system of apoptosis by growth factor deprivation on myeloma cells, we showed that the effect of Bcl-2 seemed minimal whereas Mcl-1 and
Bcl-xL were tightly
regulated by
interleukin (IL)-6
Leu et al., Oncogene 2003
(Esophageal Neoplasms) :
While Bcl-2,
Bcl-x ( L, ), and Bax were not affected, Mcl-1 was
induced by
IL-6 in human esophageal carcinoma cells
Pu et al., Prostate 2004
(Prostatic Neoplasms) :
Among Bcl-2 family proteins, only
Bcl-xL was evidently
increased by
IL-6 stimulation
Kathiria et al., Cancer Res 2012
(Colitis...) :
In wild-type p53 cells, PHB overexpression decreased basal and
interleukin-6 induced STAT3 activation and expression of the STAT3 responsive genes
Bcl-xL and Bcl-2
Oritani et al., Blood 1999
:
During this process,
IL-6 downregulated expression of BCL2 in 1A9-M cells and
stimulated BCL-XL expression, but had no effect on p53, Bax, or Bak gene expression