Gene interactions and pathways from curated databases and text-mining

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EGFR — SYP

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: Complex of GAB1-SYP → EGFR (directlyIncreases, GAB1/SYP Activity) Lehr et al., Biochemistry 2000*
    Evidence: Recently, we identified a similar cohort of tyrosine phosphorylation sites for the epidermal growth factor receptor (EGFR) with a predominant phosphorylation of tyrosine residue Y657 and binding of Syp [Lehr, S. et al. (1999) Biochemistry 38, 151-159].