Gene interactions and pathways from curated databases and text-mining

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ABL1 — ARG1

Text-mined interactions from Literome

Hawk et al., Cancer Res 2002 : We showed that the Arg to Leu mutation in the Phe-Leu-Val-Arg-Glu-Ser ( FLVRES ) sequence of the SH2 domain, known to interfere with phosphotyrosine sequence binding, did not block the binding of Bcr first exon sequences to the Abl SH2 domain
Cao et al., J Biol Chem 2003 (Breast Neoplasms) : The results further demonstrate that the interaction between c-Abl and Arg involves c-Abl mediated phosphorylation of Arg
Cao et al., Oncogene 2005 (Breast Neoplasms) : The results further demonstrate that c-Abl mediated phosphorylation of Arg on Y-261 similarly confers Arg stabilization
Ganguly et al., Genes & cancer 2012 : Accumulating evidence now indicates that c-Abl and/or Arg are activated in some solid tumor cell lines via unique mechanisms that do not involve gene mutation/translocation, and c-Abl/Arg activation promotes matrix degradation, invasion, proliferation, tumorigenesis, and/or metastasis, depending on the tumor type