Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Pizzuti et al., Diabetes 1999 (Insulin Resistance) : Plasma cell differentiation antigen ( PC-1 ) glycoprotein inhibits insulin receptor signaling and is associated with insulin resistance
Maddux et al., Diabetes 2000 (Insulin Resistance) : Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit
Takata et al., J Atheroscler Thromb 2009 (Hyperglycemia) : Alpha2-Heremans Schmid glycoprotein ( AHSG ), also known as fetuin-A, is secreted from the liver and inhibits tyrosine kinase activity of the insulin receptor
Rieger et al., Hämostaseologie 2011 (Genetic Predisposition to Disease...) : Overexpression of plasma cell membrane glycoprotein-1 ( PC-1 ) inhibits insulin receptor tyrosine kinase activity and thus favours insulin resistance and atherosclerotic vascular disease