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EGFR — PPARA

Text-mined interactions from Literome

Gardner et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Experiments with the Src inhibitor, PP2, and the antioxidant N-acetyl-L-cysteine revealed critical roles for Src and reactive oxygen species as upstream mediators of EGFR transactivation in response to PPAR ligands
Zhao et al., J Lipid Res 2012 : Further studies showed that TNF-a decreased expression of the antiapoptotic proteins Bcl-2 and Bcl-xL, decreased I?Ba and PPAR? , and also inhibited PI3K dependent Akt and EGFR signaling
Zhi et al., IUBMB Life 2012 (Adenocarcinoma, Mucinous...) : By transcription factor ( TF ) assay, CD73 was found to regulate some associated TFs activity such as PPAR?, which mediates EGFR expression, although whether PPAR? mediates the effect of CD73 on EGFR expression needs further study