Gene interactions and pathways from curated databases and text-mining

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F7 — IL8

Text-mined interactions from Literome

Zhou et al., Oncol Rep 2008 (Colonic Neoplasms...) : PAR2 agonist ( SLIGKV-NH2 ) and factor VIIa significantly stimulated SW620 cell proliferation, migratory activity, and interleukin 8 (IL-8) secretion compared to control
Zhou et al., Mol Med Report 2010 : Tissue factor-factor VIIa regulates interleukin-8 , tissue factor and caspase-7 expression in SW620 cells through protease activated receptor-2 activation ... It was found that factor VIIa ( 10 nM ) significantly increased interleukin-8 (IL-8) expression at the mRNA and protein levels, enhanced TF mRNA expression and TF activity, and decreased caspase-7 expression at the mRNA and protein levels in the SW620 cells