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PCNA — RHOA

Text-mined interactions from Literome

Teramoto et al., Oncogene 2003 : For example, H-Ras V12 upregulated osteopontin and Akt 1, and H-Ras and RhoA stimulated cyclin G1, cyclin dependent kinase 8, cyclin A2 and HMGI-C, while Rac1 QL and Cdc42 QL upregulated extracellular matrix and cell adhesion proteins such as alpha-actinin 4, procollagen type I and V and neuropilin
Hu et al., J Biol Chem 1999 : In this report, we have demonstrated that, in IIC9 cells, RhoA regulates cyclin E/CDK2 activity, which is required for p27 ( Kip ) degradation ... In the absence of serum, expression of constitutively active RhoA ( 63 ) resulted in significant stimulation of cyclin E/CDK2 activity and degradation of p27 ( Kip ) ... In addition, expression of dominant negative RhoA blocked serum induced cyclin E/CDK2 activity and p27 ( Kip ) degradation