Gene interactions and pathways from curated databases and text-mining

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FAS — VEGFA

Text-mined interactions from Literome

Marx et al., Endothelium : journal of endothelial cell research 1999 : The same effect was found with Fas-ligation, although at high concentrations Fas-ligation induced no further increase, but even a decrease of VEGF expression, possibly related to cell damage
Menendez et al., J Cell Biochem 2005 (Neoplasms) : Considering that Her-2/neu overexpression correlates with increased expression of the hypoxia inducible factor-1alpha ( HIF-1alpha ), which, in a mitogen activated protein kinase ( MAPK ) -dependent manner, plays a key role in the expression of several genes including cytokines such as vascular endothelial growth factor ( VEGF ), we hypothesized that FAS blockade should result in a concomitant down-regulation of VEGF
Infanger et al., Apoptosis 2006 : Caspase-3, Bax, Fas , and 85-kDa apoptosis related cleavage fragments were clearly reduced by VEGF
Fujiwara et al., J Dermatol 2007 (Inflammation...) : Fas mediated upregulation of vascular endothelial growth factor and monocyte chemoattractant protein-1 expression in cultured dermal fibroblasts : role in the inflammatory response