Gene interactions and pathways from curated databases and text-mining

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HMGCR — NOS2

Text-mined interactions from Literome

Sata et al., FASEB J 2001 (Ischemia) : Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia
Kolyada et al., Hypertension 2001 : We examined whether HMG-CoA reductase inhibitors affect the expression and activity of inducible NO synthase (iNOS) in cultured rat aortic vascular smooth muscle ( VSM ) cells
Yamamoto et al., Atherosclerosis 2003 : HMG-CoA reductase inhibitor enhances inducible nitric oxide synthase expression in rat vascular smooth muscle cells ; involvement of the Rho/Rho kinase pathway ... Little is known about the mechanism by which HMG-CoA reductase inhibitors affect inducible nitric oxide synthase (iNOS) expression
Huang et al., J Biomed Sci 2003 : HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages
Laufs et al., Circulation 1998 (Arteriosclerosis) : Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors