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PLAUR — RELA
Text-mined interactions from Literome
Iwamoto et al., Scand J Gastroenterol 2005
(Helicobacter Infections...) :
To evaluate the
role of transcription factor
NF-kappaB in uPA and
uPAR gene transcription with H. pylori stimulation, the effect of NF-kappaB inhibitor MG132 on H. pylori induced uPA and uPAR mRNA expression was examined
Baek et al., Oncol Rep 2008
(Carcinoma...) :
Suppression of the EGF induced uPAR promoter activity by the AP-1 decoy oligonuclotide, as well as expression vectors encoding mutated-type NF-kappaB inducting kinase and I-kappaB, confirmed that the activation of AP-1 and
NF-kappaB are
essential for the EGF induced
uPAR upregulation
Nalla et al., Cell Signal 2011
(Meningeal Neoplasms...) :
Downregulation of uPA and
uPAR , simultaneously by transfecting the cancer cells with bi-cistronic siRNA expressing plasmid ( pU )
inhibited radiation induced ERK activation, nuclear translocation of
Rel-A , NF-?B DNA binding activity, and MCP-1 expression