Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Iwamoto et al., Scand J Gastroenterol 2005 (Helicobacter Infections...) : To evaluate the role of transcription factor NF-kappaB in uPA and uPAR gene transcription with H. pylori stimulation, the effect of NF-kappaB inhibitor MG132 on H. pylori induced uPA and uPAR mRNA expression was examined
Baek et al., Oncol Rep 2008 (Carcinoma...) : Suppression of the EGF induced uPAR promoter activity by the AP-1 decoy oligonuclotide, as well as expression vectors encoding mutated-type NF-kappaB inducting kinase and I-kappaB, confirmed that the activation of AP-1 and NF-kappaB are essential for the EGF induced uPAR upregulation
Nalla et al., Cell Signal 2011 (Meningeal Neoplasms...) : Downregulation of uPA and uPAR , simultaneously by transfecting the cancer cells with bi-cistronic siRNA expressing plasmid ( pU ) inhibited radiation induced ERK activation, nuclear translocation of Rel-A , NF-?B DNA binding activity, and MCP-1 expression