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CFTR — IFNG

Text-mined interactions from Literome

Kulka et al., J Pharmacol Exp Ther 2005 : IFNgamma up-regulation of CFTR in mast cells was inhibited by p38 and extracellular signal regulated kinase ( ERK ) kinase inhibitors but not a Janus tyrosine kinase (JAK)2 inhibitor, whereas in T84 cells IFNgamma mediated down-regulation of CFTR was JAK2 dependent and ERK- and p38 independent ... This and other work suggests that the effect of IFNgamma on CFTR expression in mast cells is important for their function
Besançon et al., Am J Physiol 1994 (Cystic Fibrosis) : IFN-gamma and tumor necrosis factor-alpha synergistically reduce CFTR gene expression