Gene interactions and pathways from curated databases and text-mining

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AKT2 — IQGAP1

Text-mined interactions from Literome

Lee et al., Mol Biol Cell 2010 : We further demonstrate that disruption of specific IQGAP/cortexillin complexes, which also regulate cortical mechanics, causes extended activation of PI3K and Akt/PKB but not Ras activation
Sbroggiò et al., Cardiovasc Res 2011 (Disease Models, Animal...) : IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload