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IRF6 — ISG20
Text-mined interactions from Literome
Lin et al., Oncogene 2001
:
vIRF-1 has been shown to downregulate the interferon- and
IRF mediated transcriptional activation of
ISG and murine IFNA4 gene promoters
Chiang et al., J Immunol 2006
:
In this study we show that IRF3 mediated
ISG induction by
LPS requires the production of reactive oxygen species ( ROS ) by the NADPH dependent oxidase NOX4 ... ASK1 kinase activity proved essential for IRF3 mediated
ISG induction by
LPS