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MAGEA12 — TP53

Text-mined interactions from Literome

Marcar et al., Cancer Res 2010 (Bone Neoplasms...) : These data suggest that Mage-A may block the association of p53 with its cognate sites in chromatin ... Consistent with this idea, silencing of Mage-A expression leads to upregulation of several p53-responsive genes in a p53 dependent manner and stimulates by several fold the interaction of p53 with the p21, MDM2, and PUMA promoters
Weeraratne et al., Neuro Oncol 2011 (Cerebellar Neoplasms...) : This decrease in MAGE-A results in a concomitant increase in p53 and its associated transcriptional targets, p21/WAF1/CIP1 and, importantly, miR-34a