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PLD2 — RAC1
Text-mined interactions from Literome
Santy et al., J Cell Biol 2001
:
However, inhibition of
PLD does not
prevent activation of
Rac
Hess et al., J Biol Chem 1997
:
In contrast, in cells treated with platelet derived growth factor ( PDGF ) or phorbol ester, the wtRac1 cells showed little or no enhancement of PLD activity, and the response was not affected in the N17Rac1 cells, implying that
Rac1 played a minimal role in the activation of
PLD by PDGF or protein kinase C ... In summary, these data indicate a major
role for
Rac1 in the activation of
PLD by EGF, but not PDGF or protein kinase C