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CBL — JUN

Text-mined interactions from Literome

Rellahan et al., J Biol Chem 1997 : Cbl mediated regulation of T cell receptor induced AP1 activation ... Cbl overexpression in Jurkat T cells inhibited AP1 activity after TCR ligation ... However, AP1 induction by 4beta-phorbol 12-myristate 13-acetate, which up-regulates Ras activity in a protein kinase C-dependent, TCR/tyrosine kinase independent manner, was not affected by Cbl overexpression ... Cbl overexpression also did not affect AP1 induction by an activated Ras protein or a membrane bound form of the guanine nucleotide exchange factor Sos
Bustelo et al., Oncogene 1997 : Cbl-b , a member of the Sli-1/c-Cbl protein family, inhibits Vav mediated c-Jun N-terminal kinase activation
van Leeuwen et al., J Biol Chem 1999 : Activation of nuclear factor of activated T cells- ( NFAT ) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk ( L ) or p85 phosphatidylinositol 3-kinase association