Gene interactions and pathways from curated databases and text-mining

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ARPC4 — RAC2

Text-mined interactions from Literome

Fucini et al., Mol Biol Cell 2002 : Actin recruitment involves Cdc42/Rac and requires the activation of the Arp2/3 complex
Olazabal et al., Curr Biol 2002 : Rac and Cdc42 are required for actin and Arp2/3 complex recruitment during FcgammaR phagocytosis, while Rho controls actin assembly at CR phagosomes
Smith et al., Curr Biol 2004 : WAVE/SCAR has long been known to activate the actin nucleating Arp2/3 complex in a Rac dependent manner
Hall et al., Immunity 2006 : In addition, a Rac1/2 or Vav1/3 deficiency blocks Arp2/3 recruitment and actin polymerization at the complement induced phagosome, indicating that these proteins regulate early steps in phagocytosis
Ten Klooster et al., Biochem J 2006 : Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization