Gene interactions and pathways from curated databases and text-mining

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IGF1R — JAK1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: JAK1 → IGF1R (increases, IGF1R Activity, JAK1 Activity) Zong et al., J Biol Chem 2000*
    Evidence: tyrosine phosphorylation of STAT3, JAK1, and JAK2 was increased upon IGF-I stimulation of endogenous IGF-IR in 293T cells transfected with the respective STAT or JAK expression vector.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *