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HIPK2 — SETD2

Text-mined interactions from Literome

Nardinocchi et al., Molecular cancer 2009 : Homeodomain interacting protein kinase-2 ( HIPK2 ), a transcriptional co-repressor with apoptotic function, can affect hypoxia-inducible factor 1 (HIF-1) transcriptional activity, through downmodulation of its HIF-1alpha subunit, in normoxic condition ... Inhibition of HIF-1 transcriptional activity was dependent on HIPK2 catalytic activity
Nardinocchi et al., Aging 2011 : HIF-1a upregulation induced proteasomal degradation of homeodomain interacting protein kinase-2 ( HIPK2 ), the p53 apoptotic activator