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MAPK1 — VAV1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind_translation Interaction:
VAV1
—
MAPK1
(coimmunoprecipitation)
Lee et al., FEBS Lett 1997*
-
IRef Biogrid Interaction:
VAV1
—
MAPK1
(physical association, affinity chromatography technology)
Song et al., J Biol Chem 1996*
-
IRef Biogrid Interaction:
VAV1
—
MAPK1
(physical association, affinity chromatography technology)
Lee et al., FEBS Lett 1997*
-
IRef Hprd Interaction:
VAV1
—
MAPK1
(in vivo)
Song et al., J Biol Chem 1996*, Lee et al., FEBS Lett 1997*
-
IRef Ophid Interaction:
VAV1
—
MAPK1
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Mainiero et al., Immunity 2000
(MAP Kinase Signaling System) :
In addition, we identified some of the upstream events accompanying the beta1 integrin mediated p38
MAPK activation, namely, the
activation of the Rac guanine nucleotide exchange factor (GEF) p95
Vav , the small G protein Rac1, and the cytoplasmic kinases Pak1 and MKK3 ... Finally, we provide direct evidence that p95
Vav and Rac
control the activation of p38
MAPK triggered by beta1 integrins
O'Rourke et al., Immunity 1998
:
Interaction of CD19 with
Vav also
mediates the synergistic activation of the
mitogen activated protein kinase JNK
Miranti et al., Curr Biol 1998
:
Additionally, Syk and
Vav1 cooperatively
induced activation of Jun N-terminal kinase (JNK),
extracellular-signal regulated kinase 2 ( ERK2 ) and the kinase Akt, and phosphorylation of the oncoprotein Cbl in fibrinogen-adherent cells