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CX3CR1 — NFKB1

Text-mined interactions from Literome

Chandrasekar et al., Biochem J 2003 : TNF-alpha activated nuclear factor kappaB (NF-kappaB) and induced fractalkine and CX3CR1 expression in a time dependent manner in rat aortic SMCs. Transient transfections with dominant negative ( dn ) inhibitory kappaB (IkappaB)-alpha, dnIkappaB-beta, dnIkappaB kinase ( IKK)-gamma, kinase-dead ( kd ) NF-kappaB inducing kinase (NIK) and kdIKK-beta, or pretreatment with wortmannin, Akt inhibitor, pyrrolidinecarbodithioc acid ammonium salt ( ` PDTC ' ) or MG-132, significantly attenuated TNF-alpha induced fractalkine and CX3CR1 expression ... Taken together, our results demonstrate that TNF-alpha induces the expression of fractalkine and CX3CR1 in rat aortic SMCs and that this induction is mediated by NF-kappaB activation
Gan et al., Cell Tissue Res 2013 (Inflammation) : Inhibitors of p38MAPK, JAK-STAT, NF-kB , and AP-1 significantly reduced CX3CL1 and CX3CR1 expression