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AQP5 — PRKACB
Text-mined interactions from Literome
Yamamoto et al., Brain Res Mol Brain Res 2002
(Brain Edema) :
The dbcAMP induced effects on
AQP5 and AQP9 mRNAs were
inhibited by
PKA inhibitors
Woo et al., Biochem Biophys Res Commun 2008
:
These results indicate that, in AQP5, serine156 may be phosphorylated by
PKA , but membrane expression of
AQP5 may not be
regulated by PKA phosphorylation
Kumari et al., Molecular vision 2012
:
Effects of
phosphokinase A (PKA) agonist cyclic AMP ( cAMP ), and antagonist H-89 on
AQP5 expression and localization were studied in vitro using MDCK ( Madin-Darby Canine Kidney ) cells, and ex vivo using isolated corneas from wild type mice ... This is the first report on the spatial expression of
AQP5 in the corneal keratocytes and lens epithelial cells, as well as on the
regulation of AQP5 localization by
PKA in the corneal epithelial cells ...
PKA mediated regulation of
AQP5 holds promise for therapeutic intervention to control corneal and lens diseases