Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of KEAP1-NFE2L2
→
MAPK11
(increases, KEAP1/NFE2L2 Activity)
Keum et al., Cancer Res 2006* Evidence: stimulation of p38 MAPK isoforms phosphorylated purified Nrf2 protein and caused an increase in the interaction between Nrf2 and Keap1 in vitro and the suppression of Nrf2 translocation into the nucleus.
OpenBEL Selventa BEL large corpus:
NFE2L2
→
MAPK11
(increases, NFE2L2 Activity)
Keum et al., Cancer Res 2006* Evidence: stimulation of p38 MAPK isoforms phosphorylated purified Nrf2 protein and caused an increase in the interaction between Nrf2 and Keap1 in vitro and the suppression of Nrf2 translocation into the nucleus.