Zhang et al., Exp Cell Res 2001
(Bacterial Infections) :
In quiescent cultures, hsp60 increased ERK1/2 phosphorylation in a sustained manner and p38 phosphorylation transiently
Zanin-Zhorov et al., J Clin Invest 2006
:
The enhancing effects of HSP60 costimulation on Tregs involved innate signaling via TLR2, led to activation of PKC, PI3K, and p38 , and were further enhanced by inhibition of ERK