Reza et al., Dev Neurosci 2004
:
Our in vivo experiments suggest that Pax6 in neural retina regulates FGF8 expression, which may maintain L-Maf expression in the lens to be essential for later lens fiber differentiation
Spence et al., Molecular vision 2007
:
Retina regeneration in the chick embryo is not induced by spontaneous Mitf downregulation but requires FGF/FGFR/MEK/Erk dependent upregulation of Pax6 Reza et al., Differentiation 2007
(Microphthalmos) :
Our data suggest a new role for Pax6 in regulating FGF8 and BMP4 expression during pattern formation of the optic cup, and that a Pax6 regulated balance between FGF8 and BMP4 is critical for retinogenesis
Yoo et al., Stem Cells 2011
(MAP Kinase Signaling System) :
In this study, we asked how FGF signaling leads to PAX6 transcription and neuroectoderm specification from hESCs
Kayam et al., Development 2013
:
Finally, FGF signaling acts upstream of the Pax6-Krox20 network to regulate Pax6 segmental expression