Gene interactions and pathways from curated databases and text-mining

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JUN — NOTCH2

Text-mined interactions from Literome

Talora et al., Genes Dev 2002 (Cell Transformation, Neoplastic...) : Increased Notch1 signaling, but not Notch2 , causes a dramatic down-modulation of HPV-driven transcription of the E6/E7 viral genes, through suppression of AP-1 activity by up-regulation of the Fra-1 family member and decreased c-Fos expression
Henken et al., Cellular oncology (Dordrecht) 2012 (Cell Transformation, Neoplastic...) : Moderate Notch expression led to an increased AP-1 transcriptional activity and DNA binding activity, but did not affect complex composition
Ordentlich et al., Mol Cell Biol 1998 : We provide evidence that Notch and Deltex may act on E47 by inhibiting signaling through Ras because ( i ) full E47 activity was found to be dependent on Ras and ( ii ) both Notch and Deltex inhibited GAL4-Jun , a hybrid transcription factor whose activity is dependent on signaling from Ras to SAPK/JNK