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HDAC3 — PI3

Text-mined interactions from Literome

Alam et al., J Biol Chem 2011 (Inflammation) : Overexpression of HDAC3 induced the interaction between phosphoinositol 3-kinase (PI3K) and IFN response factor 3 (IRF3), leading to IRF3 phosphorylation, nuclear translocation, and galectin-9 expression
Moskowitz et al., Curr Oncol Rep 2012 (Hodgkin Disease) : Additional agents that have demonstrated activity in HL include histone deacetylase inhibitors, such as panobinostat, entinostat, and mocetinostat, PI3-kinase/Akt/Mtor pathway inhibitors , such as everolimus, as well as lenalidomide and bendamustine