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CDC42 — DOCK7
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Kulkarni et al., J Biol Chem 2011
:
Multiple factors confer specific
Cdc42 and Rac protein
activation by
dedicator of cytokinesis ( DOCK ) nucleotide exchange factors ...
DOCK ( dedicator of cytokinesis ) guanine nucleotide exchange factors ( GEFs )
activate the Rho-family GTPases Rac and
Cdc42 to control cell migration, morphogenesis, and phagocytosis
Harada et al., Blood 2012
:
Therefore,
DOCK8 regulates interstitial DC migration by controlling
Cdc42 activity spatially