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MITF — SKP1

Text-mined interactions from Literome

Nakajima et al., J Nat Med 2012 : Signaling analysis with immunoblots revealed that in human melanocytes or human melanoma cells treated with WSE, there was a marked deficiency in SCF stimulated phosphorylation of ERK, MITF and CREB, but not of Raf-1 and MEK
Nakajima et al., Arch Dermatol Res 2012 (Hyperpigmentation) : Real-time RT-PCR and western blotting of Ax-treated HEEs revealed that the SCF stimulated expression of tyrosinase (TYR), TYR related protein-1 (TYRP1), and Pmel17, as well as microphthalmia associated transcription factor ( MITF ), is significantly suppressed by Ax at the transcriptional and translational levels
Wakabayashi et al., J Dermatol Sci 2013 (Lentigo) : Pre-treatment of cultured normal human melanocytes with the NCMs interrupted the EDN1+SCF induced stimulation of steady-state levels of MITF at the transcriptional and translational levels and TYR activity without any direct inhibitory effect on the catalytic activity of TYR in vitro