Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Leppä et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : We investigated how JNK and c-Jun contribute to neuronal differentiation , cell survival, and apoptosis
Feng et al., Mol Cell Biol 2002 (Neuroblastoma) : Our results show that c-Jun/AP-1 , through up-regulation of NCAM140, plays an important role in both NGF induced neuronal differentiation and resistance to apoptosis induced by NO in neuroblastoma cells ... Our results show that c-Jun/AP-1 , through up-regulation of NCAM140, plays an important role in both NGF induced neuronal differentiation and resistance to apoptosis induced by NO in neuroblastoma cells
Yang et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Basic fibroblast growth factor induced neuronal differentiation of mouse bone marrow stromal cells requires FGFR-1, MAPK/ERK, and transcription factor AP-1
Leppä et al., EMBO J 1998 : Constitutively activated c-Jun , which mimics the MAPK phosphorylated form of the protein, can induce neuronal differentiation of PC12 cells independently of upstream signals ... Therefore, dual input of expression and phosphorylation of c-Jun provided by the ERK pathway is required to direct neuronal differentiation in PC12 cells