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TNF — TYR

Text-mined interactions from Literome

Englaro et al., Oncogene 1999 (Melanoma, Experimental) : First, we show that TNFalpha inhibits the activity and protein expression of tyrosinase which is the key enzyme of melanogenesis ... Furthermore, a mutant of inhibitory kappa B ( IkappaB ), that prevents NFkappaB activation, is able to revert the effect of TNFalpha on the tyrosinase promoter activity
Silveira et al., Photodermatol Photoimmunol Photomed 2008 : Coccoloba uvifera L. showed antioxidant and anti-tyrosinase activities and also inhibited the production of IL-1alpha, TNF-alpha and alpha-MSH in melanocytes subjected to UV radiation ( P < 0.01 )
Cain et al., J Cell Biol 2010 : We find that depletion of p110alpha but not other p110 isoforms decreases TNF induced endothelial permeability, Tyr phosphorylation of the adherens junction protein vascular endothelial cadherin ( VE-cadherin ), and leukocyte TEM
Swope et al., J Invest Dermatol 1994 : Previously we demonstrated that neonatal human melanocyte proliferation and tyrosinase activity are inhibited by interleukin-1 alpha, tumor necrosis factor-alpha , and interleukin-6
Martínez-Esparza et al., Eur J Biochem 1998 (Melanoma, Experimental) : Therefore, the inhibitory effect of TNF-alpha on tyrosinase and TRP-1 results from combined effect on mRNA levels and enzymatic activity or protein stability