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NOS3 — VCAM1
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
VCAM1
→
NOS3
(increases, VCAM1 Activity)
Evidence: L-NMA inhibited poly(I-C)-induced surface expression of E-selectin and VCAM-1 by 25 and 45%, respectively, and mRNA levels of E-selectin and VCAM-1
Text-mined interactions from Literome
Kawachi et al., Am J Physiol 1999
(Chronic Disease...) :
Role of inducible
nitric oxide synthase in the regulation of
VCAM-1 expression in gut inflammation
Li et al., Arterioscler Thromb Vasc Biol 2002
(Hypertension) :
The present study was undertaken to determine whether gene transfer of
endothelial NO synthase (eNOS) or manganese superoxide dismutase ( MnSOD )
affects VCAM-1 levels in arteries from hypertensive rats ... These results suggest that gene transfer of MnSOD or
eNOS suppresses arterial
VCAM-1 expression in DOCA-salt hypertension by reducing the superoxide level
He et al., Nan Fang Yi Ke Da Xue Xue Bao 2008
(Arteriosclerosis) :
Compared with the model group, the expressions of integrins-beta1, CTGF and
VCAM-1 were down-regulated and
eNOS up-regulated in EECP group
Ponnuswamy et al., PloS one 2012
(Atherosclerosis) :
eNOS deficiency
increased macrophage infiltration in carotid arteries and
vascular cell adhesion molecule-1 ( VCAM-1 ) expression, both in endothelial and smooth muscle cells