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IL10 — PRKDC
Text-mined interactions from Literome
Yotsumoto et al., J Immunol 2008
:
Endosomal translocation of CpG-oligodeoxynucleotides inhibits
DNA-PKcs dependent
IL-10 production in macrophages ... Thus, our findings suggest that
DNA-PKcs in the cytoplasm
play an important role in CpG-ODN induced production of
IL-10 in macrophages ... In addition,
DNA-PKcs mediated production of
IL-10 and IL-12 p70 can be regulated by manipulating the intracellular trafficking of CpG-ODN in macrophages
Hazeki et al., PloS one 2011
:
Phosphoinositide 3-kinase? controls the intracellular localization of CpG to limit
DNA-PKcs dependent
IL-10 production in macrophages