Gene interactions and pathways from curated databases and text-mining

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SRF — TGFB1

Text-mined interactions from Literome

Hirschi et al., J Biol Chem 2002 : CArG motifs bind transcriptional activator serum response factor ; gel shift analyses revealed increased binding of serum response factor containing complexes to this site in response to transforming growth factor-beta , paralleled by increased serum response factor protein expression
Yang et al., Am J Respir Cell Mol Biol 2003 : cDNA array analysis showed that SRFDelta5 and SRF induced expression of transforming growth factor-beta1 , a critical factor in myofibroblast differentiation
Qiu et al., J Mol Cell Cardiol 2003 : We found that TGF-beta1 transiently induces SRF and SM22 transcription, and that this process is accompanied by transient increases of SRF and Smad3 binding to the SM22 promoter
Kawai-Kowase et al., Arterioscler Thromb Vasc Biol 2004 : TGFbeta1 increased SRF expression through an increase in transcription of the SRF gene ... Transient transfection assays showed that bFGF significantly suppressed induction of the SM22alpha promoter-driven luciferase activity by TGFbeta1, whereas bFGF had no effects on the TGFbeta1 mediated increase in SRF expression and SRF : DNA binding activity
Sato et al., Arterioscler Thromb Vasc Biol 2005 : PP1 also inhibited the TGF-beta1 induced expression of serum response factor (SRF) , a transcription factor regulating the SMC marker gene expression
Paradis et al., J Biol Chem 1996 : Induction of the promoter by transforming growth factor beta or norepinephrine requires serum response factor (SRF) and TEF-1 ; expression is inhibited by YY1