Couty et al., J Neurochem 2007
:
In the present study, we show that, whereas PECAM-1 is known to control positively the trans-endothelial migration of leukocytes via homophilic interactions between leukocytes and endothelial cells, PECAM-1 engagement on brain endothelial surface unexpectedly counteracts the ICAM-1 induced tyrosine phosphorylation of cortactin and rearrangements of the actin cytoskeleton
Durieu-Trautmann et al., J Biol Chem 1994
:
Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton associated protein cortactin in brain microvessel endothelial cells