Pei et al., Neurosci Lett 2005
(Brain Ischemia) :
The antioxidant N-acetylcysteine (NAC) could inhibit the translocation of MLK3 from cytosolic fraction to the membrane fraction and decrease the interactions of MLK3 and PSD-95 in the membrane fraction
Zhang et al., Neurosci Lett 2006
(Brain Ischemia...) :
Results indicate that NAC distinctly inhibited the association of PSD95 with GluR6 and MLK3 , the autophosphorylation of MLK3, the combination of MLK3 with JNK3 and JNK3 activation