Gene interactions and pathways from curated databases and text-mining

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AGTR1 — NPPA

Text-mined interactions from Literome

Hu et al., Basic Res Cardiol 2001 (Myocardial Infarction) : The effects of angiotensin converting enzyme (ACE) inhibition ( quinapril, 6 mg/kg/day ) and angiotensin II type 1 (AT1) receptor blockade ( losartan, 10 mg/kg/day ) on ANP levels in 18 selected, microdissected brain nuclei were determined in sham operated rats and rats with left ventricular dysfunction 8 weeks after myocardial infarction ( MI )
Zavala et al., J Renin Angiotensin Aldosterone Syst 2004 : The activation of brain angiotensinergic neurons and stimulation of AT1- receptors may stimulate the release of ANP to the circulation
Oh et al., Peptides 2011 (Cardiomyopathy, Hypertrophic...) : Therefore, we suggest that Ang II generated endogenously by atrial stretch suppresses stretch induced ANP secretion through the AT1 receptor and alteration of Ang II effect in 2K1C rat may be due to upregulation of AT1 receptor
Park et al., Peptides 2013 : The stimulated effect of Ang III ( 1µM ) on stretch induced ANP secretion was blocked by the pretreatment of Ang II type 2 (AT2) receptor antagonist but not by AT1 or Mas receptor antagonist
Leskinen et al., Circ Res 1997 : These results indicate that combined inhibition of ETA/B and AT1 receptors almost completely blocks ANP response to acute volume load
Soualmia et al., J Cardiovasc Pharmacol 1997 : We concluded that Ang II induced IP production and ANP release through AT1 receptors