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CDKN1A — ETS1
Text-mined interactions from Literome
Zhang et al., J Biol Chem 2003
:
Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1
: ETS-1 regulates basal and and inducible
p21WAF1/Cip : ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis acting elements in the p21WAF/Cip1 promoter ... Using transient transfection and Western blot analysis, we determined that
Ets-1 activates
p21WAF1/Cip1 transcription and protein expression ... The phenotypic importance of
Ets-1 regulation of
p21WAF1/Cip1 was demonstrated by the capacity of antisense p21WAF1/Cip1 strategies to block Ets-1-inhibition of apoptosis and inhibit Ets-1-induction of proliferation
von Brandenstein et al., Life Sci 2012
(Carcinoma, Renal Cell...) :
ETS dependent p16INK4a and
p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells