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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CDKN1A — ETS1

Text-mined interactions from Literome

Zhang et al., J Biol Chem 2003 : Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1 : ETS-1 regulates basal and and inducible p21WAF1/Cip : ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis acting elements in the p21WAF/Cip1 promoter ... Using transient transfection and Western blot analysis, we determined that Ets-1 activates p21WAF1/Cip1 transcription and protein expression ... The phenotypic importance of Ets-1 regulation of p21WAF1/Cip1 was demonstrated by the capacity of antisense p21WAF1/Cip1 strategies to block Ets-1-inhibition of apoptosis and inhibit Ets-1-induction of proliferation
von Brandenstein et al., Life Sci 2012 (Carcinoma, Renal Cell...) : ETS dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells