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STAT1 — TPO

Text-mined interactions from Literome

Erhardt et al., Exp Hematol 2009 (Thrombocytopenia) : In signal transduction studies of washed human platelets, eltrombopag induced the phosphorylation signal transducers and activators of transcription ( STAT ) proteins with no phosphorylation of Akt, whereas recombinant human TPO ( rhTPO ) induced the phosphorylation of Akt as well as STAT-1 , -3, and -5
Pallard et al., EMBO J 1995 (Leukemia, Megakaryoblastic, Acute) : We demonstrated that TPO activates the kinase JAK2 and a STAT5-like transcriptional factor but not STAT1 , STAT2, STAT3 or STAT4, in a very rapid and transient manner
Brizzi et al., J Clin Invest 1997 : We demonstrate that PMN express the TPO receptor c-Mpl and that TPO induces STAT1 tyrosine phosphorylation and the formation of a serum inducible element complex containing STAT1