◀ Back to IL8

FAS — IL8

Text-mined interactions from Literome

Hagimoto et al., Am J Respir Cell Mol Biol 1999 : Induction of interleukin-8 secretion and apoptosis in bronchiolar epithelial cells by Fas ligation ... In this study we investigated whether Fas ligation induces IL-8 secretion in addition to apoptosis in bronchiolar epithelial cells in vitro
Verhagen et al., Cytokine 2001 (Colonic Neoplasms) : TNF and CD95 promote IL-8 gene transactivation via independent elements in colon carcinoma cells ... While the IL-8 promotor elements activated by TNF are well characterised, those responsible for induction of IL-8 by CD95 are unknown ... Nevertheless, IL-8 induction by CD95 resulted primarily from increased transcription and not from an increase in IL-8 mRNA stability ... These results suggest that promoter elements/enhancers involved in CD95 mediated IL-8 induction are distinct from those used by TNF and not contained within the 1.6 kb region immediately upstream of the initiation codon
Shimada et al., J Gastroenterol Hepatol 2001 (Adenocarcinoma...) : The pretreatment with interferon (IFN)-gamma markedly enhanced the effects of Fas Ag stimulation ; IFN-gamma pretreatment and Fas Ag stimulation synergistically induced not only apoptosis but also IL-8 and MCP-1 secretion
Saas et al., Neuroreport 2002 (Encephalitis) : It was previously shown that astrocytes are resistant to Fas mediated death, responding to Fas triggering by interleukin-8 production
Shin et al., Yonsei Med J 2002 (Carcinoma, Hepatocellular...) : Conclusively, TGF-beta2, IL-8 and MCP-1 were overexpressed in HBV associated hepatoma cells, and the expressions of chemokines were not increased by Fas ligation in human hepatoma cells
O'Brien et al., Ann N Y Acad Sci 2002 (MAP Kinase Signaling System) : Activation of the p38 MAPK and ERK1/2 pathways is required for Fas induced IL-8 production in colonic epithelial cells ... This paper aims to examine the contribution of all three of the MAP kinase signaling pathways to Fas induced IL-8 up-regulation in HT29 colon epithelial cells
Yamaoka-Tojo et al., Coron Artery Dis 2003 : Fas neutralizing agent ( Fas-Fc ) suppressed the Fas mediated secretions of IL-8 and MCP-1 ( P < 0.01 ) both as well as the Fas mediated apoptosis ... On the other hand, whereas Z-IETD-FMK suppressed apoptosis, the inhibitor enhanced the Fas mediated secretions of both IL-8 and MCP-1 beyond the value of the Fas stimulation alone ( P < 0.01 ), suggesting an enhanced signalling for the chemokine expression
Brat et al., Neuro Oncol 2005 (Brain Neoplasms...) : In addition to hypoxia/anoxia stimulation, increased IL-8 in gliomas occurs in response to Fas ligation, death receptor activation, cytosolic Ca ( 2+ ), TNF-alpha, IL-1, and other cytokines and various cellular stresses
Koshika et al., Inflamm Res 2006 (Inflammation...) : Both Fas and A23187 caused significant IL-8 expression and cell death in A549 cells
Scheller et al., J Neural Transm Suppl 2006 : Moreover, CD95 triggered expression of IL-4 and IL-8 when caspase activity was inhibited, but not in the absence of ZVAD
Chang et al., Experimental biology and medicine (Maywood, N.J.) 2009 : Taken together, the production of IL-8 by SPE B in A549 cells is mediated by Fas , and followed by the activation of FADD, caspase 8, MEKK1, ERK and NF-kappaB
Cullen et al., Mol Cell 2013 : Fas induced production of MCP-1 and IL-8 promoted chemotaxis of phagocytes toward apoptotic cells, suggesting that these factors serve as `` find-me '' signals in this context
Cesaratto et al., PloS one 2013 : E3330 treatment prevented the functional activation of NF-?B via the alteration of APE1 subcellular trafficking and reduced IL-6 and IL-8 expression induced by TNF-a and FAs accumulation through blockage of the redox mediated activation of NF-?B
Abreu-Martin et al., J Immunol 1995 (Second Messenger Systems) : The experiments presented here demonstrate that Fas Ag ligation alone led to production of IL-8 by colonic epithelial cells and represented another function mediated by Fas Ag in addition to apoptosis ... This study shows that the pathways leading to cell death and IL-8 production in response to Fas Ag ligation and TNF-alpha were similar with regard to their requirements for new gene expression, protein synthesis, and protein kinase activity
Sekine et al., Biochem Biophys Res Commun 1996 (Arthritis, Rheumatoid) : Fas mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CPP32 mediated apoptosis
Yamada et al., Diabetologia 1996 (Autoimmune Diseases...) : Mouse islet cell lysis mediated by interleukin-1 induced Fas