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IL5 — IL8
Text-mined interactions from Literome
Suchin et al., J Am Acad Dermatol 2001
(Eosinophilia...) :
Increased
interleukin 5 production in eosinophilic Sézary syndrome :
regulation by interferon alfa and
interleukin 12
Lottaz et al., J Invest Dermatol 2001
:
We hypothesize that inhibition of this pathway prevents secretion of interleukin-1, thereby downregulating
interleukin-1 dependent autocrine induction of
interleukin-8
Prause et al., Eur J Pharmacol 2003
:
Pharmacological modulation of
interleukin-17 induced GCP-2-, GRO-alpha- and
interleukin-8 release in human bronchial epithelial cells ... We found that
interleukin-17 ( 1-1000 ng/ml )
increased the release of GCP-2, GRO-alpha and
interleukin-8 in a concentration dependent manner
Waehre et al., J Am Coll Cardiol 2003
(Coronary Artery Disease) :
Our main findings were : 1 ) gene expression of several chemokines ( i.e., macrophage inflammatory protein [MIP ] -1alpha, MIP-1beta, and
interleukin [ IL]-8 ) and chemokine receptors ( i.e., CC chemokine receptor [ CCR]1, CCR2, CCR4, and CCR5 ) was markedly increased among CAD patients compared with healthy control subjects ; 2 ) treatment with atorvastatin and simvastatin markedly reduced the mRNA levels of some of these chemokines ( i.e., MIP-1alpha, MIP-1beta, IL-8 ) and receptors ( i.e., CCR1 and CCR2 ), with the most pronounced effect in the atorvastatin group ; and 3 ) statin therapy
reduced the spontaneous release of
IL-8 and MIP-1alpha from PBMCs in CAD patients
Vittori et al., J Allergy Clin Immunol 1992
:
Protective effect of nedocromil sodium on the
interleukin-1 induced production of
interleukin-8 in human bronchial epithelial cells
Uchiyama et al., Am J Obstet Gynecol 1992
:
These results indicate that
interleukin-8-like chemotactic factor participates in the cervical ripening at term pregnancy and that the production of this factor is
controlled effectively by
interleukin-1
Warringa et al., Am J Respir Cell Mol Biol 1992
(Asthma) :
We have investigated the modulatory
role of
IL-5 on N-formyl-methionyl-leucyl-phenylalanine ( FMLP ), neutrophil activating factor (
NAF/IL-8 ), platelet factor 4 (PF4), and cytokine induced chemotaxis of eosinophils from normal individuals
Soloff et al., Endocrinology 2004
:
In situ analysis of
interleukin-1 induced transcription of cox-2 and
il-8 in cultured human myometrial cells
Wuyts et al., J Heart Lung Transplant 2004
:
N-acetylcysteine inhibits
interleukin-17 induced
interleukin-8 production from human airway smooth muscle cells : a possible role for anti-oxidative treatment in chronic lung rejection ?
Hirota et al., Rheumatol Int 1992
:
Production of
interleukin 8 by cultured synovial cells in
response to
interleukin 1 and tumor necrosis factor
Hashmi et al., Coron Artery Dis 2006
(Angina, Unstable) :
Role of interleukin-17 and
interleukin-17 induced cytokines interleukin-6 and
interleukin-8 in unstable coronary artery disease
Galatowicz et al., Clin Exp Allergy 2007
(Conjunctivitis, Allergic...) :
For conjunctival biopsy derived cultures ( n=11 ), FcepsilonR1 stimulation increased histamine, TNF-alpha, TNF-beta,
IL-5 and IL-8 levels and the production of IL-5, IL-6 ( P < 0.05 ), histamine and
IL-8 ( P < 0.01 ) was
inhibited by epinastine
Darbonne et al., J Clin Invest 1991
:
Their binding of IL-8 is rapidly reversible and does not result in receptor internalization, although bound IL-8 is resistant to extraction by pH 3 buffer at 5 degrees C.
125I-IL-8 binding to red cells was not
inhibited by epidermal growth factor or
interleukin 1, but was inhibited by monocyte chemotactic peptide-1, which is not a neutrophil chemotaxin, but is a member of the same family of polypeptides as IL-8
Larsen et al., Biochem Biophys Res Commun 1991
:
1,25 ( OH ) 2-D3 is a potent regulator of
interleukin-1 induced
interleukin-8 expression and production
Hua et al., Molecular oral microbiology 2010
(Periodontal Diseases) :
Furthermore, as little as 2 µg ml(-1) mPE was sufficient to inhibit
interleukin-1ß induced secretion of
interleukin-8 in both gingival epithelial cells and THP-1 cells
Vindeløv et al., Growth Horm IGF Res 2011
(Adenoma...) :
Interleukin-8 production from human somatotroph adenoma cells is
stimulated by
interleukin-1ß and inhibited by growth hormone releasing hormone and somatostatin
Strieter et al., Am J Respir Cell Mol Biol 1990
:
The
induction of AMO derived
IL-8 by tumor necrosis factor (TNF), lipopolysaccharide (LPS), and
interleukin-1 ( IL-1 beta ) was shown to be both dose and time dependent
Swain et al., Proc Natl Acad Sci U S A 1981
:
We conclude that the C.C3.11.75
TRF activity is not
due to
interleukin 1 or to interleukin 2 but to a third factor provisionally designated as ( DL ) TRF
Zaitseva et al., Infect Immun 1995
:
Gamma interferon ( IFN-gamma ),
interleukin-2 (IL-2), IL-4, and
IL-5 induction was assayed by mRNA-specific PCR and by enzyme linked immunosorbent assay and bioassay for protein production
Ng et al., J Biol Chem 1994
:
Although tumor necrosis factor (TNF) and
interleukin-1 ( IL ) induce the expression of the
IL-8 , TNF stimulated gene 6, and plasminogen activation inhibitor-2 genes and the activation of NF-kappa B with nearly identical kinetics, the two cytokines differ significantly in the induction of the IL-6 gene in all primary fibroblasts tested
Nakajima et al., J Immunol 1996
:
Release of
IL-8 protein and storage of IL-4 and IL-10 proteins were
enhanced by exogenous
IL-5 and inhibited by a transcription inhibitor, actinomycin D. Degranulation of stored granule proteins was not affected by actinomycin D
Hedges et al., Cytokine 1996
:
IL-5 , IL-12, IL-13 and TGF-beta 1 additively enhanced the bacterially induced IL-6 secretion, but they did not
affect IL-8 secretion
Miyamasu et al., Allergy 1997
:
Because eosinophilopoietic factors are known to stimulate various functions of eosinophils, we examined the
effect of
interleukin (IL)-5 on chemoattractant induced
IL-8 generation from eosinophils ... Although
IL-5 alone
induced little or no
IL-8 production from eosinophils, short-term preincubation with IL-5 markedly enhanced the eosinophil IL-8 generation caused by C5a plus cytochalasin B ( CB )
Rudack et al., Laryngorhinootologie 1998
(Chronic Disease...) :
These findings suggest that
IL-8 plays a pivotal role in neutrophil dominated and
IL-5 in eosinophil dominated sinusitis
Krakauer et al., J Infect Dis 1998
:
Interleukin-8 production by human monocytic cells in response to staphylococcal exotoxins is direct and
independent of
interleukin-1 and tumor necrosis factor-alpha