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JUN — MUC2
Text-mined interactions from Literome
Alcaide et al., Eur J Immunol 2004
(Chagas Disease) :
Furthermore, AgC10 inhibition must lie upstream in the MAPK activation pathway by LPS, since this
mucin also
inhibited extracellularly regulated kinase (ERK) and
Jun kinase (JNK)activation
Gensch et al., J Biol Chem 2004
:
Tobacco smoke control of
mucin production in lung cells
requires oxygen radicals
AP-1 and JNK
Song et al., Gastroenterology 2005
(Colonic Neoplasms) :
Electrophoretic mobility shift assays, site directed mutagenesis, and chromatin immunoprecipitation were used to monitor the
participation of
AP-1 in
MUC2 transcription ... Mutation in the AP-1 site markedly decreased
MUC2 promoter activity, and MUC2 transcription was
inhibited by cotransfection with a dominant negative
AP-1 vector
Lim et al., American journal of translational research 2009
:
Ras-Raf1-ERK1/2 dependent
AP-1 activation positively
regulates MUC5AC
mucin induction by S. pneumoniae, whereas MEKK3-JNK1/2 dependent AP-1 activation negatively regulates it