◀ Back to STAT3

IFNA1 — STAT3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: STAT3 → IFNA1 (increases)
  Evidence: The transactivation of wild type Stat3 was strongly increased by IFN-alpha from 2-fold to 7-fold.

Text-mined interactions from Literome

Zhang et al., Exp Eye Res 2005 : Retinas from embryonic and neonatal stages showed that STAT3 but not STAT1 was activated in response to ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), fibroblast growth factor-1 (FGF1), fibroblast growth factor-2 (FGF2), epidermal growth factor (EGF), interferon-alpha ( IFN-alpha ) and interferon-gamma (IFN-gamma) in distinct patterns
Humpoliková-Adámková et al., Eur J Cancer 2009 (Disease Progression...) : Using Western blot analyses, we show that interferon-alpha stimulated STAT3 phosphorylation at tyrosine ( Y705 ) residue in 17 % of cases
Sengupta et al., Proc Natl Acad Sci U S A 1998 : In contrast to IL-6, activation of Stat3 by interferon-alpha was not inhibited