Gene interactions and pathways from curated databases and text-mining

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ANPEP — HMOX1

Text-mined interactions from Literome

Lin et al., Am J Pathol 2010 (Drug-Induced Liver Injury...) : Herein, we demonstrate a novel functional PPRE in the promoter regions of HO-1, and APN mediated HO-1 induction elicited an antiapoptotic effect and a decrease in iron deposition in hepatocytes subjected to iron challenge
Cheng et al., J Cell Physiol 2012 (Acute Kidney Injury...) : Furthermore, APN induced HO-1 expression was only found in wild-type but not in PPARa gene deleted mice ... This provides in vivo evidence that APN mediated HO-1 expression depends on PPARa regulation