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BCR — EGR1

Text-mined interactions from Literome

Fukada et al., J Biol Chem 2001 : The binding of Egr-1 to PRS is suppressed by p210 Bcr-Abl due to the inhibition of Egr-1 expression, resulting in the enhancement of PTP1B promoter activity
Ke et al., J Biol Chem 2006 (Lymphoma, B-Cell...) : Cross linking of the B cell receptor (BCR) on the immature B lymphoma cell line BKS-2 induces growth inhibition and apoptosis accompanied by rapid down-regulation of the immediate-early gene egr-1 ... Our study suggests that BCR signals reduce egr-1 expression by inhibiting activation of ERK and JNK
Boukhiar et al., Experimental hematology & oncology 2013 : Inhibition of JNK with SP600125 induced apoptosis and reduced level of basal and BCR induced expression of EGR-1 ... Treatment with PP2 or with dasatinib suppressed BCR induced LYN and JNK phosphorylation as well as EGR-1 upregulation and is associated with a decrease of cell survival in all cases analysed
Maltzman et al., J Exp Med 1996 : We have investigated BCR induced expression of the Icam-1 gene in primary B cells and B cell lines and have found it to be dependent on BCR induced expression of the transcription factor EGR1